Hormoz Ayromlou; Parisa Pourvahed; Fatemeh Jahanjoo; Homayoun Dolatkhah; Seyyed Kazem Shakouri; Neda Dolatkhah
Volume 20, Issue 11 , November 2018, , Pages 1-12
Abstract
Background: Antioxidants are considered essential components in neurodegenerative disease management since they can protect cells from oxidative damage. Objectives: The current study aimed at evaluating the intake and serum level of selected antioxidants in subjects possessing mild cognitive impairment ...
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Background: Antioxidants are considered essential components in neurodegenerative disease management since they can protect cells from oxidative damage. Objectives: The current study aimed at evaluating the intake and serum level of selected antioxidants in subjects possessing mild cognitive impairment (MCI) compared with a cognitively intact control.Methods: The current prospective, case-control study was conducted in Tabriz from December 2016 to August 2017 on a total of 45 patients with MCI as a case group and another 45 healthy subjects matched by age and gender were recruited for the control group. After completing the mini-mental state examination (MMSE-12) questionnaire, the cases with MCI were identified using the modified Peterson standard. By a semi-quantitative food frequency questionnaire (FFQ), the common dietary intakes during the previous year were recorded and blood samples were collected.Results: Of the 90 subjects in the current study, 61% were male and 39% female, with the mean age of 68.8 ± 5.5 years. There were no significant differences between the two groups with respect to dietary intakes of vitamin C, beta-carotene, and lycopene (P = 0.079, P = 0.413, and P = 0.455, respectively). The results of the studied parameters showed that serum beta-carotene and lycopene (P = 0.004 and P = 0.044, respectively) in healthy subjects were significantly higher than those of the elderly people with MCI. There was a significant correlation between Vitamin C dietary intake and serum level and cognitive scores in MMSE-12 (r = 0.231, P = 0.028 and r = 0.224, P = 0.033, respectively) and also between serum level of lycopene and cognitive scores(r = 0.388, P = 0.000). Conclusions: The subjects with mild cognitive impairment had a significantly lower serum levels of lycopene beta-carotene antiox- idants compared with healthy subjects, and there was a positive correlation between serum level of vitamin C and lycopene and also vitamin C dietary intake and scores in the MMSE-12 test.
Mohammad Rahbar; Fariba Eslamian; Vahideh Toopchizadeh; Fatemeh Jahanjoo; Ali Kargar; Neda Dolatkhah
Volume 20, Issue 9 , September 2018, , Pages 1-10
Abstract
Background: Plantar fasciitis (PF) is the most common cause of metatarsus pain. Objectives: The current study aimed at comparing the improvement of pain and function in patients with PF treated with extracor- poreal shockwave (ESWT) and dry-needling therapy. Methods: The current single-blinded, clinical ...
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Background: Plantar fasciitis (PF) is the most common cause of metatarsus pain. Objectives: The current study aimed at comparing the improvement of pain and function in patients with PF treated with extracor- poreal shockwave (ESWT) and dry-needling therapy. Methods: The current single-blinded, clinical study was conducted on 72 patients with PF selected from the outpatient and rehabil- itation clinics of Tabriz University of Medical Sciences, Tabriz, Iran from August 2016 to March 2017. Patients were randomly divided into two groups, and the subjects in the first group were treated with ESWT, while the second group were treated with dry-needling. The performance was evaluated based on FFI (Foot Function Index), and the pain level according to VAS (Visual Analogue Scale); subjects were evaluated at baseline, as well as four and eight weeks after treatment and the obtained results were compared and analyzed using appropriate statistical methods. Results: The subjects’ VAS and FFI scores significantly decreased compared with those of the baseline in both dry-needling and ESWT groups four and eight weeks after treatment (P < 0.005). Based on the criteria, no statistically significant difference was observed between the two groups four weeks after the treatment (P = 0.732 for VAS and P = 0.578 for FFI). However, eight weeks after treatment, significant changes were observed in pain reduction and FFI in the dry-needling group compared with the ESWT group (VAS: 1.7 ± 0.9 vs. 2.9 ± 1.9, P = 0.013 and FFI: 31.4 ± 28.0 vs. 50.4 ± 33.1, P = 0.008, respectively). Conclusions: Both extracorporeal shockwave and dry-needling therapies were effective in plantar fasciitis treatment; despite the fact that the results of the current study revealed that dry-needling therapy was more effective than extracorporeal shockwave, at eight weeks after treatment.
Majid Hajifaraji; Fatemeh Jahanjou; Fatemeh Abbasalizadeh; Naser Aghamohammadzadeh; Mehran Mesgari Abbasi; Neda Dolatkhah
Volume 19, Issue 6 , June 2017, , Pages 1-10
Abstract
Background: Despite progress in the control and treatment of gestational diabetes mellitus (GDM) in pregnant females, these patients remain at risk of disease complications.Objectives: The present study aimed at investigating the effect of probiotic supplements on Systolic Blood Pressure (SBP) and Diastolic ...
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Background: Despite progress in the control and treatment of gestational diabetes mellitus (GDM) in pregnant females, these patients remain at risk of disease complications.Objectives: The present study aimed at investigating the effect of probiotic supplements on Systolic Blood Pressure (SBP) and Diastolic Blood Pressure (DBP) in pregnant females diagnosed with GDM.Methods: This randomized double-blind, placebo-controlled trial randomly assigned 64 pregnant females with GDM, recruited through convenience sampling, to either a group receiving a probiotic capsule (n = 32) or a group receiving a placebo (n = 32) for 8 weeks in Tabriz, Iran, during the spring and summer months of 2014. Their blood pressure was measured at baseline and at 2-week intervals, up to 8 weeks.Results: A total of 56 subjects completed the study. There was no significant difference in SBP in the probiotic group at any time compared with that at onset, yet, SBP increased significantly in the placebo group. The declining trend of DBP was evident in the probiotic group at 2 weeks and continued to the end of the study; however, DBP had increased slightly by week 6 in the placebo group. There were significant differences between the probiotic and placebo groups at 6 and 8 weeks, respectively, for SBP (104.828 (2.051) mmHg vs. 112.963 (2.126) mmHg; P = 0.008) and (106.552 (1.845) mmHg vs. 115.185 (1.912) mmHg; P = 0.002) and for DBP (62.414 (1.353) mmHg vs. 70.741 (1.402) mmHg; P < 0.001) and (60.690 (1.540) mmHg vs. 71.296 (1.596) mmHg; P < 0.0010).Conclusions: The results demonstrated that consumption of probiotic supplements for 8 weeks prevented an increase in SBP and decreased DBP in pregnant females diagnosed with GDM.